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Medication Guide
During Pregnancy

Pregnant women may safely use the following over-the-counter (OTC) medications. Please follow the directions on the package for adult dosage and use. Generic substitutions are OK. If taking other medications, please consult with your doctor first .  *Avoid the use of all essential oils and herbal supplements, including Elderberry syrup/supplements. 

At any time during your pregnancy, it is NOT OK to consume:

  • Alcohol
  • Beer
  • Wine
  • Marijuana
  • Street Drugs
  • Cigarettes
  • e-Cigarettes


  • Aspirin products (unless instructed by MD)
  • Ibuprofen (Advil)
  • Naproxen (Aleve)

If you have any further questions about a medication, be sure to ask your nurse or OB-GYN doctor.

Download a copy of our Medication Guide During Pregnancy for an easy reference, or bookmark this page. 

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Problem Over-the-Counter Medications Call Your Obstetrician If You Have
Mild Headaches/Aches & Pains Tylenol (Acetaminophen) 325 mg
Extra Strength Tylenol (Acetaminophen) 500 mg - DO NOT exceed 3000mg a day
Severe and/or Persistent Headaches
Nasal Congestion/Cough Due to a Cold, Sinusitis

Afrin Nasal Spray (for 3 days only)
Mucinex (guaifenesin)
Neti Pot
Saline Nasal Spray
Plain Robitussin
Vicks Vapo Rub
Emergen-C Original
Cold Eeze

OK to use after first trimester (14 weeks 0 days) and beyond:
Pseudoephedrine (plain Sudafed)

Not recommended in pregnancy unless approved by your doctor:
Phenylephrine (Sudafed PE or other PE drugs)

Please ask the pharmacist while at the store if unable to find the safe options. 


No Relief
Heartburn Tums
Pepcid as directed

No Relief


If taking Nexium or omeprazole prior, then consult MD


Ginger tablets 250-500 mg 2-3 times daily Vitamin B6 25mg tablet 3-4 times per day (no more than 200 mg/day)  Unisom with active ingredient of Doxylamine 25 mg tablet, ½ tablet (12.5 mg) 2 times/day or full tablet at bedtime, may cause drowsiness

No Relief
Sore throat

Alcohol-Free Lozenges


Severe or persistent sore throat

Colace Stool Softener
Milk of Magnesia

Severe straining
Gas Gas-X (Simethicone) No Relief
Hemorrhoids Anusol HC Cream/Ointment
Chilled Witch Hazel Packs
Sitz Bath
Tucks Pads
Preparation H Cream/Ointment
Bleeding or severe pain
Insomnia Warm Bath
Warm Milk
Vitamin B6 (50 mg)
Benadryl (25 mg)
Tylenol PM
Unisom, 1 Tablet (25 mg) 
No Relief
Symptoms of vaginal yeast  3-7 days Monistat treatment No relief call for appointment to evaluate

Nasacort Short Term-Afrin (for 3 days only)
Benadryl (may cause drowsiness)
Claritin (plain-no “D”)
Zyrtec (plain-no “D”)

No relief with plain antihistamines.
Sore muscles Icy Hot
Tylenol (Acetaminophen) 325mg
Extra Strength Tylenol is OK too (Acetaminophen) 500 mg
Heat pad on low (do not place directly over your abdomen).
No Relief



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